Margo Georgiadis

Margo Georgiadis is a CEO-Partner at Flagship Pioneering and Co-Founder and CEO of Montai Therapeutics. In these roles, Margo brings extensive expertise in technological innovation and high-performance business transformation and leverages her artificial intelligence and machine learning experience to advance biotech innovation. Working with Flagship CEO and Founder Noubar Afeyan and Lord Ara Darzi, she plays an instrumental role in Flagship’s efforts to scale its Preemptive Medicine & Health Initiative and develop new companies aimed at deterring or delaying the onset of disease, improve health outcomes for consumers, corporations, and countries.

Margo is an experienced CEO and company builder who has dedicated her career to transforming products and services with data and technology to empower consumers to live better lives, and to deliver outsized growth and returns for investors. Most recently, she served as an Endurance Partner at venture catalyst firm General Catalyst, where she focused on building next-generation healthcare platforms that improve clinical outcomes while making healthcare more consumer-centric, accessible and affordable. Previously, she served as President and CEO of Ancestry where she brought together content, science, and technology to transform Ancestry into the undisputed global leader in family history and consumer genomics. Under her leadership, the company scaled to over 3.6M subscribers, doubled its genomics network to over 20M customers and delivered over $1B in subscription revenue with record setting profitability and cash flow.

Margo also spent nine years at Google as President of Americas and Vice President of Global Operations, leading the hyper scaling of Google’s commercial operations and advertising sales across all digital solutions including search, mobile, video, shopping, local and commerce, and platforms. Her other operating roles include serving as the CEO of Mattel, Inc., the COO of Groupon, EVP of US Card Services and CMO at Discover Financial Services, and as a partner at McKinsey and Company.

Beyond her operating roles, Margo is an experienced investor at the intersection of health and technology and has helped to scale multiple successful platform companies as an Endurance Partner at General Catalyst and a Managing Partner at Synetro Group.

Margo has received multiple awards for her business and community leadership including the Forbes “Excellence Award in Innovation,” Chicago Innovation’s “Visionary Award,” the Eastman Medal from the University of Rochester, Executive of the Year in Utah, and was named to Crain’s “Most Powerful Women in Business” and Fortune’s “50 Most Powerful Women in Business” lists.

Margo serves on multiple Boards including McDonald’s, Applovin, Ro, Handshake, the Parker Institute for Cancer Immunotherapy and People’s Health Clinic. She earned a BA in Economics from Harvard College and an MBA from Harvard Business School.